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NFL Week 7 ‘Monday Night Football’ game picks and open thread

Week 7 of the 2023 NFL season wraps up with Monday Night Football featuring a battle between two 2022 NFC playoff teams heading in different directions: the San Francisco 49ers (5-1) and the Minnesota Vikings (2-4). Read on for our picks and predictions.

San Francisco 49ers v Minnesota Vikings Photo by Michael Zagaris/San Francisco 49ers/Getty Images

Week 7 of the 2023 NFL season is in the books, save tonight’s Monday Night Football matchup between the San Francisco 49ers (5-1) and the Minnesota Vikings (2-4). While this week’s slate didn’t feature quite the same level of crazy as Week 6, it was pretty close. We got the New England Patriots upsetting the Buffalo Bills, a crazy 39-38 Cleveland Browns victory over the Indianapolis Colts, and a 16-13 slop fest between our Atlanta Falcons and the Tampa Bay Buccaneers for control of the NFC South.

Let’s get right to tonight’s pick, which I’ll be making on a straight moneyline (aka picking the winner) basis. I’ll still provide the information on the spread and over/under, for those interested. At the bottom, I’ll show the rest of the staff’s picks for the game.

All odds are taken from DraftKings Sportsbook and are subject to change. See the current odds here.

Monday Night Football: San Francisco 49ers (5-1) at Minnesota Vikings (2-4)

The pick: 49ers (-290)

Spread: 49ers -7 | Over/Under: 43.5 | Moneyline: 49ers -290, Vikings +260

Last week’s Monday Night Football game was a close affair, and one of the better MNF games of the season. This week we get an angry, embarrassed 49ers team coming off an inexplicable loss to the P.J. Walker-led Browns going up against a disheveled Vikings team and primetime Kirk Cousins. This one has the makings of a massive blowout, but even if it’s not, give me the 49ers all day.

Staff picks

What are your picks and predictions for tonight’s Monday Night Football matchup?

Odds/lines subject to change. T&Cs apply. See for details.