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NFL Week 4 ‘Monday Night Football’ game picks and open thread

Week 4 of the 2023 NFL season wraps up with Monday Night Football featuring a clash of two NFC playoff teams from 2022: the Seattle Seahawks (2-1) taking on the New York Giants (1-2). Read on for our picks and predictions.

New York Giants v Seattle Seahawks Photo by Lindsey Wasson/Getty Images

The fourth week of the 2023 NFL season is coming to a close, and while it didn’t feature as many of the absurdly lopsided scores as we saw in Week 3, there were a number of surprises and entertaining games. We witnessed a pair of overtime contests, with the Los Angeles Rams topping the Indianapolis Colts and the Philadelphia Eagles defeating the Washington Commanders. We also saw a spicier-than-expected Sunday Night Football matchup between the Kansas City Chiefs and the New York Jets.

This week, we’re back to a single Monday Night Football game, as the Seattle Seahawks (2-1) take on the New York Giants (1-2).

Let’s get right to tonight’s pick, which I’ll be making on a straight moneyline (aka picking the winner) basis. I’ll still provide the information on the spread and over/under, for those interested. At the bottom, I’ll show the rest of the staff’s picks for the game.

All odds are taken from DraftKings Sportsbook and are subject to change. See the current odds here.

Monday Night Football: Seattle Seahawks (2-1) at New York Giants (1-2)

The pick: Seahawks -105

Spread: Seahawks -2 | Over/Under: 47 | Moneyline: Seahawks -105, Giants +110

Both of these NFC playoff teams from 2022 suffered double-digit losses in the opening week of the season, but only one has shown much life since. The Seahawks at least have their high-powered offense to lean on, and have since put up 37 points in back-to-back games. New York, meanwhile, has continued to struggle outside of a miraculous comeback against the Cardinals. I’m going with the more inspiring and more fun team in Seattle.

Staff picks

What are your picks and predictions for tonight’s Monday Night Football matchup?

Odds/lines subject to change. T&Cs apply. See for details.