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QB Matt Ryan
Ryan's game against Washington was concerning, and inarguably one of the worst efforts of his career. I would tend to view it as a blip, and while his season numbers are officially underwhelming, Ryan remains a solid play against a lackluster Saints defense. Maybe not a true QB1, but in the neighborhood.
QB Drew Brees
I don't think Brees is going to have a great week, but I do expect him to toss a couple of touchdowns and put some real yards on the board, even if it's in garbage time. If you had both, I'd still go with Ryan, but Brees isn't a bad play at all this week.
RB Devonta Freeman
Monitor his injury status, but Freeman is a locked-and-loaded RB1 if he's healthy, and he should run roughshod over New Orleans. Get him in your lineup.
RB C.J. Spiller
Spiller hasn't done much thus far in 2015, but he's a speedy pass-catching back and the Falcons are likely to slow down Mark Ingram. He could very well bust out against the Falcons, who still have trouble defending backs of his ilk.
WR Leonard Hankerson
Unquestionably the team's top receiving option with Julio Jones potentially out, even if he's mixed quiet weeks with quality ones thus far. I think he could very easily top 100 yards in this one.
WR Brandin Cooks
He's had a relatively pedestrian year, but Marques Colston is dealing with an injury, Brees has to throw to somebody, and Cooks is shifty enough to cause problems over the middle. WR4/FLEX, more than likely, but a name to keep in mind.
TE Jacob Tamme
If Julio sits, Tamme is the other obvious beneficiary. I could see him reeling in a touchdown and putting 60-plus yards on the board, making him a fine play at a barren tight end position.
I mean...if you're feeling like rolling the dice? The Saints could get going a bit and are a lock to put up garbage time points and yardage if they fall behind big, but if you like the team's chances of hitting Drew Brees a bunch and picking up a handful of turnovers, go for it.
WR Julio Jones
Can't believe I'm putting him here, but that's what injuries will do. I doubt Julio will be 100% if he plays, but there indications that he's going to be in this one, and you can't afford to leave him out of your lineup entirely if he's active.
RB Mark Ingram
He's been generally kind of average, Khiry Robinson may be stealing his carries, and if Sean Payton's smart he'll use Spiller at the expense of Ingram against the Falcons' defense, given the matchup. Sit him.
You can't expect Ryan to be that quiet for a second straight week, Freeman and/or Tevin Coleman are capable of racking up the yards, and the Falcons could absolutely drop 30-plus points on this defense if they're firing on all cylinders. Extremely risky play.