Those of you unfamiliar with the 370 curse check this article out, it was written after Ricky Williams retired and is quite old but still relevant (you have to scroll down a bit for the table)
Those running backs who have had over 370 carries have seen dramatic fall offs the next season and beyond. Ask Shaun Alexander. This has happened more than once.
Michael Turner is the only RB currently on par to break the 370 mark - 332 carries with 23.7 carries per game and 2 games left. (380 carries)
Adrian Peterson is the only other RB that can come close - 320 carries with 22.9 carries per game and 2 games left. (366)